A-485

Catalog No.: A16830

p300/CBP inhibitor

A-485

A-485 Chemical Structure

CAS NO. 1889279-16-6

A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and 3 nM in a CBP TR-FRET assay with selectivity > 1000-fold over closely related HATs.

Availability: In stock

Package Price Qty
2 mg
$120.00
5 mg
$205.00
10 mg
$360.00
50 mg
$1,400.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and 3 nM in a CBP TR-FRET assay with selectivity > 1000-fold over closely related HATs.
In vitro DMSO 89 mg/mL (165.9 mM)
Water Insoluble
Ethanol 89 mg/mL (165.9 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.64 mL 93.2 mL 186.4 mL
0.5 mM 3.73 mL 18.64 mL 37.28 mL
1 mM 1.86 mL 9.32 mL 18.64 mL
5 mM 0.37 mL 1.86 mL 3.73 mL

*The above data is based on the productmolecular weight 536.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16830
Actions Inhibitor
CAS No. 1889279-16-6
Formula C25H24F4N4O5
M. Wt 536.48
Purity >98%
Synonyms A 485, A485
SMILES O=C(N1CC(N([[email protected]](C(F)(F)F)C)CC2=CC=C(F)C=C2)=O)[[email protected]@]3(OC1=O)CCC4=CC(NC(NC)=O)=CC=C43
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy A-485 | A-485 Supplier | purchase | cost | manufacturer | order | distributor | buy 1889279-16-6| 1889279-16-6 Supplier | purchase 1889279-16-6 | 1889279-16-6 cost | 1889279-16-6 manufacturer | order 1889279-16-6 | 1889279-16-6 distributor
Rewards