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A 740003 is a novel competitive antagonist of P2X7 receptors (IC50 values = 40 nM for human and 18 nM for rat).
| In vitro | DMSO | 85 mg/mL (179.11 mM) | |
| Water | Insoluble | ||
| Ethanol | 1 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.07 mL | 105.35 mL | 210.7 mL |
| 0.5 mM | 4.21 mL | 21.07 mL | 42.14 mL |
| 1 mM | 2.11 mL | 10.54 mL | 21.07 mL |
| 5 mM | 0.42 mL | 2.11 mL | 4.21 mL |
*The above data is based on the productmolecular weight 474.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11316 |
|---|---|
| Actions | Antagonist |
| CAS No. | 861393-28-4 |
| Formula | C26H30N6O3 |
| M. Wt | 474.6 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | A740003, A-740003 |
| SMILES | CC(C)(C)C(NC(=O)CC1=CC(=C(C=C1)OC)OC)/N=C(/NC#N)\NC2=CC=CC3=C2C=CC=N3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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