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Biological Activity
A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.92 mL | 174.62 mL | 349.25 mL |
| 0.5 mM | 6.98 mL | 34.92 mL | 69.85 mL |
| 1 mM | 3.49 mL | 17.46 mL | 34.92 mL |
| 5 mM | 0.7 mL | 3.49 mL | 6.98 mL |
*The above data is based on the productmolecular weight 286.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14436 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 607737-87-1 |
| Formula | C18H14N4 |
| M. Wt | 286.33 |
| Purity | >98% |
| Synonyms | A77-01 |
| SMILES | CC1=CC=CC(=N1)C2=C(C=NN2)C3=CC=NC4=CC=CC=C34 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Contact information
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