A 77-01

Catalog No.: A14436

ALK5 inhibitor

A 77-01

A 77-01 Chemical Structure

CAS NO. 607737-87-1

A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.

Availability: In stock

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10 mg

Regular Price: $80.00

Special Price $64.00

25 mg

Regular Price: $150.00

Special Price $120.00

50 mg

Regular Price: $250.00

Special Price $200.00

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Biological Activity

A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.92 mL 174.62 mL 349.25 mL
0.5 mM 6.98 mL 34.92 mL 69.85 mL
1 mM 3.49 mL 17.46 mL 34.92 mL
5 mM 0.7 mL 3.49 mL 6.98 mL

*The above data is based on the productmolecular weight 286.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14436
Actions Inhibitor
CAS No. 607737-87-1
Formula C18H14N4
M. Wt 286.33
Purity >98%
Synonyms A77-01
SMILES CC1=CC=CC(=N1)C2=C(C=NN2)C3=CC=NC4=CC=CC=C34
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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