A-837093 sodium is a potent inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase, exhibiting high selectivity and oral bioavailability. It demonstrates strong inhibitory activity against HCV genotypes 1a (IC50 = 1.25 nM) and 1b (IC50 = 0.33 nM). A-837093 sodium has shown antiviral efficacy in in vivo studies involving HCV-infected chimpanzees, making it a valuable tool for research focused on HCV infection and therapeutic development.
A-837093 sodium is a potent inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase, exhibiting high selectivity and oral bioavailability. It demonstrates strong inhibitory activity against HCV genotypes 1a (IC50 = 1.25 nM) and 1b (IC50 = 0.33 nM). A-837093 sodium has shown antiviral efficacy in in vivo studies involving HCV-infected chimpanzees, making it a valuable tool for research focused on HCV infection and therapeutic development.
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