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A-9758 is a RORγ ligand and a potent, selective RORγt inverse agonist (IC50=5 nM), and exhibits robust potency against IL-17A release.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.96 mL | 94.81 mL | 189.62 mL |
| 0.5 mM | 3.79 mL | 18.96 mL | 37.92 mL |
| 1 mM | 1.9 mL | 9.48 mL | 18.96 mL |
| 5 mM | 0.38 mL | 1.9 mL | 3.79 mL |
*The above data is based on the productmolecular weight 527.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A19078 |
|---|---|
| Actions | Agonist |
| M. Wt | 527.36 |
| Formula | C25H23Cl2F3N2O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2055271-22-0 |
| Synonyms | A9758, A 9758 |
| SMILES | O=C(C1CCN(C(C2=CC=C(Cl)C(CC(N3C)=CC4=C3C=C(C(F)(F)F)C=C4C)=C2Cl)=O)CC1)O |
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