α,β-Methylene-ATP trisodium

Catalog No.: A67883
P2X3/P2X7 Receptor Ligand
α,β-Methylene-ATP trisodium is a potent agonist of P2X3 and P2X7 receptors, which facilitates significant biological responses through purinergic receptor activation. This compound is capable of traversing the blood-brain barrier, thereby influencing both peripheral and central nervous system pathways. It is instrumental in studying reflex cardiovascular responses and antinociceptive mechanisms mediated by noradrenergic neurons in the locus coeruleus. Researchers utilize α,β-Methylene-ATP trisodium for insights into neuropathic pain mechanisms and cardiovascular reflex regulation.
Grouped product items
Size Price Stock Qty
1mg
$20.00
In stock
5mg
$105.00
In stock
10mg
$195.00
In stock
25mg
$470.00
In stock
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionα,β-Methylene-ATP trisodium is a potent agonist of P2X3 and P2X7 receptors, which facilitates significant biological responses through purinergic receptor activation. This compound is capable of traversing the blood-brain barrier, thereby influencing both peripheral and central nervous system pathways. It is instrumental in studying reflex cardiovascular responses and antinociceptive mechanisms mediated by noradrenergic neurons in the locus coeruleus. Researchers utilize α,β-Methylene-ATP trisodium for insights into neuropathic pain mechanisms and cardiovascular reflex regulation.
Product Information
Catalog NumA67883
FormulaC11H15N5Na3O12P3
Molecular Weight571.15
CAS Number1343364-54-4
SMILESO=P(O)([O])OP(CP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C3=NC=NC(N)=C3N=C2)O1)(O[Na])=O)(O[Na])=O.[Na]
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