α-Tubulin (residues 440–451) functions as a microtubule growth inhibitor by transiently interacting with the longitudinal polymerization interface of α-tubulin. This interaction effectively regulates the association and dissociation rates of tubulin at the growing ends of microtubules, leading to inhibited microtubule growth. This reagent can be utilized in studies exploring microtubule dynamics, cellular morphology, and potential therapeutic targets for diseases associated with abnormal microtubule formation.
α-Tubulin (residues 440–451) functions as a microtubule growth inhibitor by transiently interacting with the longitudinal polymerization interface of α-tubulin. This interaction effectively regulates the association and dissociation rates of tubulin at the growing ends of microtubules, leading to inhibited microtubule growth. This reagent can be utilized in studies exploring microtubule dynamics, cellular morphology, and potential therapeutic targets for diseases associated with abnormal microtubule formation.
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