A1AR antagonist 2 is a potent antagonist of the A1 adenosine receptor (A1AR), exhibiting inhibitory constants (Kis) of 1.49 nM for hA1, 10.2 nM for hA2A, and 50.1 nM for hA2B. This compound is valuable for research applications focused on the modulation of adenosine signaling pathways and their effects on physiological and pathological processes. Its selective inhibition of A1AR makes it a useful tool in pharmacological studies involving cardiovascular, neurological, and metabolic research.
A1AR antagonist 2 is a potent antagonist of the A1 adenosine receptor (A1AR), exhibiting inhibitory constants (Kis) of 1.49 nM for hA1, 10.2 nM for hA2A, and 50.1 nM for hA2B. This compound is valuable for research applications focused on the modulation of adenosine signaling pathways and their effects on physiological and pathological processes. Its selective inhibition of A1AR makes it a useful tool in pharmacological studies involving cardiovascular, neurological, and metabolic research.
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