AB-680

Name: AB-680
Brand: Adooq Bioscience
SKU: A18534
Rating: 5 (288 reviews)

Catalog No.: A18534

CD73 inhibitor

AB-680 is highly potent, reversible and selective small molecule inhibitor of CD73 (an ecto-nucleotidase), with a Ki of 4.9 pM for hCD73, displays >10,000-fold selectivity over related ecto-nucleotidases CD39. Anti-tumor activity.

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Grouped product items
Size	Price	Stock
1mg	$110.00	In stock
2mg	$155.00	In stock
5mg	$240.00	In stock
10mg	$385.00	In stock
25mg	$650.00	In stock
50mg	$930.00	In stock
100mg	$1,265.00	In stock
*10mM 1mL in DMSO**	$310.00	In stock
Bulk Size	Bulk Discount

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Adooq Products cited in reputable paper

Biological Activity

Description	AB-680 is highly potent, reversible and selective small molecule inhibitor of CD73 (an ecto-nucleotidase), with a Ki of 4.9 pM for hCD73, displays >10,000-fold selectivity over related ecto-nucleotidases CD39. Anti-tumor activity.

Product Information

Catalog Num	A18534
Formula	C20H24ClFN4O9P2
Molecular Weight	580.82
CAS Number	2105904-82-1
SMILES	O=P(CP(O)(O)=O)(O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(Cl)C=C3N[C@H](C4=CC=CC=C4F)C)=C3C=N2)O1
Synonyms	AB680, AB 680
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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