ABT-751 (E-7010)

Catalog No.: A10024
Microtubule Associated inhibitor
ABT-751 is an antimitotic agent, inhibits microtubule polymerization, binds to β-tubulin on the colchine site; blocks cell cycle at G2M phase and induces apoptosis.
Grouped product items
Size Price Stock Qty
5mg
$35.00
In stock
10mg
$55.00
In stock
25mg
$115.00
In stock
50mg
$175.00
In stock
100mg
$285.00
In stock
200mg
$540.00
In stock
10mM * 1mL in DMSO
$35.00
In stock
Bulk Size
Bulk Discount
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Important Notice: For research use only. We do not sell to patients.

Adooq Products cited in reputable paper
Biological Activity
Discription ABT-751 is an antimitotic agent, inhibits microtubule polymerization, binds to β-tubulin on the colchine site; blocks cell cycle at G2M phase and induces apoptosis.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
Product Information
Catalog Num A10024
Formula C18H17N3O4S
Molecular Weight 371.4
CAS Number 141430-65-1
SMILES COC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=C(C=C3)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 71 mg/mL (191.16 mM)
Water Insoluble
Ethanol 12 mg/mL (32.3 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.93 mL 134.63 mL 269.25 mL
0.5 mM 5.39 mL 26.93 mL 53.85 mL
1 mM 2.69 mL 13.46 mL 26.93 mL
5 mM 0.54 mL 2.69 mL 5.39 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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