AC-099 hydrochloride

Catalog No.: A62169
NPFF2R/1R Agonist
AC-099 hydrochloride is a selective full agonist of the neuropeptide FF receptor 2 (NPFF2R) with an EC50 of 1189 nM, and a partial agonist of NPFF1R with an EC50 of 2370 nM. This compound has demonstrated the ability to attenuate hypersensitivity induced by spinal nerve ligation in rat models. AC-099 hydrochloride is valuable for research focusing on pain modulation and the neuropeptide signaling pathways associated with nociception.
Grouped product items
Size Price Stock Qty
5mg
$35.00
In stock
10mg
$55.00
In stock
25mg
$80.00
In stock
50mg
$105.00
In stock
100mg
$165.00
In stock
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
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Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionAC-099 hydrochloride is a selective full agonist of the neuropeptide FF receptor 2 (NPFF2R) with an EC50 of 1189 nM, and a partial agonist of NPFF1R with an EC50 of 2370 nM. This compound has demonstrated the ability to attenuate hypersensitivity induced by spinal nerve ligation in rat models. AC-099 hydrochloride is valuable for research focusing on pain modulation and the neuropeptide signaling pathways associated with nociception.
Product Information
Catalog NumA62169
FormulaC9H9Cl2F3N4
Molecular Weight301.10
CAS Number849335-07-5
SMILESFC(C1=CC(/C=N/NC(N)=N)=CC=C1Cl)(F)F.[H]Cl
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