AC-099 is a selective agonist for the neuropeptide FF receptor 2 (NPFF2R) with an EC50 of 1189 nM and a partial agonist for NPFF1R, exhibiting an EC50 of 2370 nM. This compound demonstrates significant potential in modulating pain responses, as evidenced by its ability to attenuate spinal nerve ligation-induced hypersensitivity in rat models. AC-099 serves as a valuable tool in pain research and for exploring the roles of NPFF receptors in the central nervous system.
AC-099 is a selective agonist for the neuropeptide FF receptor 2 (NPFF2R) with an EC50 of 1189 nM and a partial agonist for NPFF1R, exhibiting an EC50 of 2370 nM. This compound demonstrates significant potential in modulating pain responses, as evidenced by its ability to attenuate spinal nerve ligation-induced hypersensitivity in rat models. AC-099 serves as a valuable tool in pain research and for exploring the roles of NPFF receptors in the central nervous system.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
