AC 253

Name: AC 253
Brand: Adooq Bioscience
SKU: A78324
Rating: 5 (288 reviews)

Catalog No.: A78324

Amylin Antagonist

AC 253 is an amylin antagonist that specifically inhibits the binding of 125I-adrenomedullin, demonstrating an IC50 value of 25 nM. This compound is valuable for research applications focused on metabolic disorders and neurodegenerative diseases, where modulation of amylin pathways may play a critical role.

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Size	Price	Stock	Qty
1mg	$230.00	In stock
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Biological Activity

Description	AC 253 is an amylin antagonist that specifically inhibits the binding of 125I-adrenomedullin, demonstrating an IC50 value of 25 nM. This compound is valuable for research applications focused on metabolic disorders and neurodegenerative diseases, where modulation of amylin pathways may play a critical role.

Product Information

Catalog Num	A78324
Formula	C122H196N40O39
Molecular Weight	2847.11
CAS Number	151804-79-4
Sequence	Ac-Leu-Gly-Arg-Leu-Ser-Gln-Glu-Leu-His-Arg-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2
Sequence shortening	Ac-LGRLSQELHRLQTYPRTNTGSNTY-NH2
SMILES	C([C@H](CC1=CC=C(O)C=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC(C)C)NC(C)=O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CO)=O)CCC(N)=O)=O)CCC(O)=O)=O)CC(C)C)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCC(N)=O)=O)[C@@H](C)O)=O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(N)=O)=O)[C@@H](C)O)=O)CC(N)=O)=O)CO)=O)=O)[C@@H](C)O)=O)CC(N)=O)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)CCC3

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