AC-42 is a selective allosteric agonist for the M1 muscarinic receptor, exhibiting potent activity with EC50 values of 805 nM for the human wild-type and 220 nM for the Y381A mutant receptor. This compound enhances inositol phosphate (IP) accumulation and calcium mobilization in CHO cells, making it a valuable tool for studying M1 receptor signaling pathways. Its unique mechanism of action facilitates research into neuropharmacology and cognitive function modulation.
AC-42 is a selective allosteric agonist for the M1 muscarinic receptor, exhibiting potent activity with EC50 values of 805 nM for the human wild-type and 220 nM for the Y381A mutant receptor. This compound enhances inositol phosphate (IP) accumulation and calcium mobilization in CHO cells, making it a valuable tool for studying M1 receptor signaling pathways. Its unique mechanism of action facilitates research into neuropharmacology and cognitive function modulation.
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