Ac-MBP (1-11)

Catalog No.: A46236
BMP Encephalitogenic Epitope
Ac-MBP (1-11) is a synthetic peptide that represents the primary encephalitogenic epitope derived from myelin basic protein (MBP). This peptide is critical for studies on multiple sclerosis and other autoimmune disorders, as it plays a significant role in immune response and T cell activation. Ac-MBP (1-11) is widely utilized in research to understand the mechanisms of demyelination and to explore potential therapeutic interventions.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAc-MBP (1-11) is a synthetic peptide that represents the primary encephalitogenic epitope derived from myelin basic protein (MBP). This peptide is critical for studies on multiple sclerosis and other autoimmune disorders, as it plays a significant role in immune response and T cell activation. Ac-MBP (1-11) is widely utilized in research to understand the mechanisms of demyelination and to explore potential therapeutic interventions.
Product Information
Catalog NumA46236
FormulaC2H3K2OPS3
Molecular Weight248.41
CAS Number125366-42-9
SequenceAc-Ala-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys
Sequence shorteningAc-ASQKRPSQRSK
SMILESC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)C)=O)CO)=O)CCC(N)=O)=O)CCCCN)=O)CCCNC(=N)N)(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CO)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CO)=O)CCC1
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