Acid-PEG4-S-PEG4-acid

Catalog No.: A82987
PROTAC Linker
Acid-PEG4-S-PEG4-acid is a polyethylene glycol (PEG)-based linker designed for use in PROTAC (proteolysis-targeting chimeras) synthesis. This compound facilitates the formation of a novel therapeutic modality that harnesses the ubiquitin-proteasome system for targeted protein degradation. Its unique structure enhances solubility and connectivity, making it a valuable tool for researchers investigating selective protein modulation and degradation pathways.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAcid-PEG4-S-PEG4-acid is a polyethylene glycol (PEG)-based linker designed for use in PROTAC (proteolysis-targeting chimeras) synthesis. This compound facilitates the formation of a novel therapeutic modality that harnesses the ubiquitin-proteasome system for targeted protein degradation. Its unique structure enhances solubility and connectivity, making it a valuable tool for researchers investigating selective protein modulation and degradation pathways.
Product Information
Catalog NumA82987
FormulaC22H42O12S
Molecular Weight530.63
CAS Number2055041-21-7
SMILESO=C(O)CCOCCOCCOCCOCCSCCOCCOCCOCCOCCC(O)=O
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