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Biological Activity
Afegostat D-tartrate was an experimental drug for the treatment of certain forms of Gaucher's disease. The substance was used in form of the tartrate. Isofagomine (IFG) is an acid β-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.64 mL | 168.2 mL | 336.41 mL |
| 0.5 mM | 6.73 mL | 33.64 mL | 67.28 mL |
| 1 mM | 3.36 mL | 16.82 mL | 33.64 mL |
| 5 mM | 0.67 mL | 3.36 mL | 6.73 mL |
*The above data is based on the productmolecular weight 297.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14385 |
|---|---|
| CAS No. | 957230-65-8 |
| Formula | C10H19NO9 |
| M. Wt | 297.26 |
| Purity | >98% |
| Synonyms | Isofagomine D-Tartrate, D-Isofagomine, iso-Fagomine, isofagomine |
| SMILES | C1[[email protected]@H]([[email protected]]([[email protected]@H](CN1)O)O)CO.[[email protected]]([[email protected]@H](C(=O)O)O)(C(=O)O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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