AI-10-49

Name: AI-10-49
Brand: Adooq Bioscience
SKU: A15521
Rating: 5 (288 reviews)

Catalog No.: A15521

CBFBeta-SMMHC / RUNX1 inhibitor

AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM,

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AI-10-49 1256094-72-0 CBFBeta-SMMHC / RUNX1 inhibitor

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Grouped product items
Size	Price	Stock
2mg	$25.00	In stock
5mg	$50.00	In stock
10mg	$80.00	In stock
25mg	$165.00	In stock
50mg	$250.00	In stock
100mg	$375.00	In stock
200mg	$530.00	In stock
*10mM 1mL in DMSO**	$75.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Adooq Products cited in reputable paper

Biological Activity

Description

AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM,

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A15521
Formula	C30H22F6N6O5
Molecular Weight	660.52
CAS Number	1256094-72-0
SMILES	C1=CC2=C(C=C1OC(F)(F)F)NC(=N2)C3=NC=C(C=C3)OCCOCCOC4=CN=C(C=C4)C5=NC6=C(N5)C=C(C=C6)OC(F)(F)F
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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