Ald-Ph-amido-C2-PEG2-amine

Catalog No.: A83665
PROTAC Linkers
Ald-Ph-amido-C2-PEG2-amine is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the effective conjugation of E3 ligase recruiters and protein targets, enhancing the chemical degradation of specific proteins within the cell. It is particularly useful in chemical biology studies aimed at developing novel therapeutic strategies through targeted protein degradation.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAld-Ph-amido-C2-PEG2-amine is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the effective conjugation of E3 ligase recruiters and protein targets, enhancing the chemical degradation of specific proteins within the cell. It is particularly useful in chemical biology studies aimed at developing novel therapeutic strategies through targeted protein degradation.
Product Information
Catalog NumA83665
FormulaC14H20N2O4
Molecular Weight280.32
CAS Number2055013-56-2
SMILESO=C(NCCOCCOCCN)C1=CC=C(C=O)C=C1
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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