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Ald-Ph-amido-C2-PEG2-amine

PROTAC Linkers

Ald-Ph-amido-C2-PEG2-amine is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the effective conjugation of E3 ligase recruiters and protein targets, enhancing the chemical degradation of specific proteins within the cell. It is particularly useful in chemical biology studies aimed at developing novel therapeutic strategies through targeted protein degradation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2055013-56-2
Applications	PROTAC Linkers
Formula	C₁₄H₂₀N₂O₄
Molecular Weight	280.32
SMILES	O=C(NCCOCCOCCN)C1=CC=C(C=O)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.