Ald-Ph-amido-PEG3-C2-NH2

Catalog No.: A83114
PROTAC Linker
Ald-Ph-amido-PEG3-C2-NH2 is a PEG-based linker specifically designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the formation of bifunctional molecules that promote the targeted degradation of proteins via the ubiquitin-proteasome system. Its unique structure enhances the solubility and stability of PROTAC constructs, making it a valuable tool for researchers exploring protein modulation and degradation pathways in cellular studies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAld-Ph-amido-PEG3-C2-NH2 is a PEG-based linker specifically designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the formation of bifunctional molecules that promote the targeted degradation of proteins via the ubiquitin-proteasome system. Its unique structure enhances the solubility and stability of PROTAC constructs, making it a valuable tool for researchers exploring protein modulation and degradation pathways in cellular studies.
Product Information
Catalog NumA83114
FormulaC16H24N2O5
Molecular Weight324.37
CAS Number1404111-56-3
SMILESO=C(NCCOCCOCCOCCN)C1=CC=C(C=O)C=C1
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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