Alestramustine

Catalog No.: A55010
Microtubule/Tubulin
Alestramustine is an antineoplastic cytostatic agent that primarily targets microtubules by binding to microtubule-associated proteins and β-tubulin via its active metabolites. This interaction disrupts microtubule function, leading to the inhibition of cell division. Alestramustine is utilized in research applications aimed at understanding cancer cell proliferation and the mechanisms of microtubule dynamics.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAlestramustine is an antineoplastic cytostatic agent that primarily targets microtubules by binding to microtubule-associated proteins and β-tubulin via its active metabolites. This interaction disrupts microtubule function, leading to the inhibition of cell division. Alestramustine is utilized in research applications aimed at understanding cancer cell proliferation and the mechanisms of microtubule dynamics.
Product Information
Catalog NumA55010
FormulaC26H36Cl2N2O4
Molecular Weight511.48
CAS Number139402-18-9
SMILESN[C@@H](C)C(O[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=C(C=CC(OC(N(CCCl)CCCl)=O)=C4)[C@@]3([H])CC[C@]12C)=O
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