AM-0561 is a potent NIK inhibitor with a Ki of 0.3 nM, effectively suppressing the activity of the non-canonical NF-κB signaling pathway. By inhibiting NIK, AM-0561 significantly reduces p52 protein levels, which may contribute to the regulation of various cellular processes. This reagent is useful for research applications aimed at understanding NF-κB signaling in inflammation, immune response, and cancer biology.
AM-0561 is a potent NIK inhibitor with a Ki of 0.3 nM, effectively suppressing the activity of the non-canonical NF-κB signaling pathway. By inhibiting NIK, AM-0561 significantly reduces p52 protein levels, which may contribute to the regulation of various cellular processes. This reagent is useful for research applications aimed at understanding NF-κB signaling in inflammation, immune response, and cancer biology.
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