AMG 548

Catalog No.: A10970

p38 MAPK inhibitor

AMG 548 Chemical Structure

CAS NO. 864249-60-5

AMG 548 is a potent and selective inhibitor of p38α. It displays >1000-fold selectivity against 36 other kinases, and it inhibits whole blood LPS-stimulated TNFα.

Availability: In stock

Package Price Qty
5 mg
$150.00
10 mg
$250.00
50 mg
$800.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AMG 548 is a potent and selective inhibitor of p38α. It displays >1000-fold selectivity against 36 other kinases, and it inhibits whole blood LPS-stimulated TNFα.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.67 mL 108.33 mL 216.66 mL
0.5 mM 4.33 mL 21.67 mL 43.33 mL
1 mM 2.17 mL 10.83 mL 21.67 mL
5 mM 0.43 mL 2.17 mL 4.33 mL

*The above data is based on the productmolecular weight 461.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10970
Actions Inhibitor
M. Wt 461.56
Formula C29H27N5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 864249-60-5
Synonyms AMG-548, AMG548
SMILES O=C1N(C)C(NC[[email protected]](CC2=CC=CC=C2)N)=NC(C3=CC=NC=C3)=C1C4=CC=C5C(C=CC=C5)=C4

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