AMG131 benzenesulfonate

Catalog No.: A40109
PPARγ Agonist
AMG131 benzenesulfonate is a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist, classified as a non-thiazolidinedione (TZD) modulator. It binds to the PPARγ receptor, occupying a unique position in the binding pocket, which allows for distinct interactions compared to traditional TZDs. This compound has demonstrated potential in research pertaining to the treatment of type-2 diabetes mellitus, making it a valuable tool for investigating PPARγ-related metabolic pathways.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAMG131 benzenesulfonate is a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist, classified as a non-thiazolidinedione (TZD) modulator. It binds to the PPARγ receptor, occupying a unique position in the binding pocket, which allows for distinct interactions compared to traditional TZDs. This compound has demonstrated potential in research pertaining to the treatment of type-2 diabetes mellitus, making it a valuable tool for investigating PPARγ-related metabolic pathways.
Product Information
Catalog NumA40109
FormulaC27H18Cl4N2O6S2
Molecular Weight672.38
CAS Number849738-78-9
SMILESO=S(O)(C1=CC=CC=C1)=O.O=S(NC2=CC(Cl)=C(C(Cl)=C2)OC3=CN=C4C=CC=CC4=C3)(C5=CC=C(C=C5Cl)Cl)=O
SynonymsINT131 benzenesulfonate
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