Amino-PEG12-amine

Catalog No.: A82166
PROTAC Linkers
Amino-PEG12-amine is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This linker facilitates the conjugation of targeting moieties and E3 ligase recruiters, enhancing the development of targeted protein degradation strategies. Its hydrophilic properties and adjustable length make it particularly suitable for optimizing PROTAC pharmacokinetics and efficacy in various biological applications.
Grouped product items
Size Price Stock Qty
25mg
$25.00
In stock
50mg
$80.00
In stock
100mg
$130.00
In stock
250mg
$220.00
In stock
500mg
$325.00
In stock
1g
$515.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAmino-PEG12-amine is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This linker facilitates the conjugation of targeting moieties and E3 ligase recruiters, enhancing the development of targeted protein degradation strategies. Its hydrophilic properties and adjustable length make it particularly suitable for optimizing PROTAC pharmacokinetics and efficacy in various biological applications.
Product Information
Catalog NumA82166
FormulaC26H56N2O12
Molecular Weight588.73
CAS Number361543-12-6
SMILESNCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
SynonymsH2N-PEG12-CH2CH2NH2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2