Aminooxy-PEG8-acid

Catalog No.: A83771
PROTAC Linker
Aminooxy-PEG8-acid is a PEG-based linker designed for Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the construction of PROTACs by providing a versatile connection to E3 ligases and target proteins. Its enabling role in the development of targeted protein degradation strategies makes it a valuable tool in chemical biology research, especially for studying protein dynamics and therapeutic interventions.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAminooxy-PEG8-acid is a PEG-based linker designed for Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the construction of PROTACs by providing a versatile connection to E3 ligases and target proteins. Its enabling role in the development of targeted protein degradation strategies makes it a valuable tool in chemical biology research, especially for studying protein dynamics and therapeutic interventions.
Product Information
Catalog NumA83771
FormulaC19H39NO11
Molecular Weight457.51
CAS Number2055269-60-6
SMILESO=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCON
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2