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$0.00 - Nobuo Aikawa, .et al. A Novel Screening Test to Predict the Developmental Toxicity of Drugs Using Human Induced Pluripotent Stem Cells, J Toxicol Sci, 2020, 45(4):187-199 PMID: 32238694
Biological Activity
Aminopterin is an antineoplastic drug. It works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.71 mL | 113.53 mL | 227.07 mL |
| 0.5 mM | 4.54 mL | 22.71 mL | 45.41 mL |
| 1 mM | 2.27 mL | 11.35 mL | 22.71 mL |
| 5 mM | 0.45 mL | 2.27 mL | 4.54 mL |
*The above data is based on the productmolecular weight 440.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11787 |
|---|---|
| CAS No. | 54-62-6 |
| Formula | C19H20N8O5 |
| M. Wt | 440.4 |
| Purity | >98% |
| Synonyms | 4-aminopteroic acid |
| SMILES | C1=CC(=CC=C1C(=O)N[[email protected]@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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