Aminopterin

Catalog No.: A11787

Aminopterin

Aminopterin Chemical Structure

CAS NO. 54-62-6

Aminopterin is an antineoplastic drug. It works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase.

Availability: In stock

Package Price Qty
50 mg
$120.00
100 mg
$200.00
500 mg
$600.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning WARNING: Attention California Residents: This product can expose you to chemicals including Aminopterin , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Nobuo Aikawa, .et al. A Novel Screening Test to Predict the Developmental Toxicity of Drugs Using Human Induced Pluripotent Stem Cells, J Toxicol Sci, 2020, 45(4):187-199 PMID: 32238694

Biological Activity

Aminopterin is an antineoplastic drug. It works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.71 mL 113.53 mL 227.07 mL
0.5 mM 4.54 mL 22.71 mL 45.41 mL
1 mM 2.27 mL 11.35 mL 22.71 mL
5 mM 0.45 mL 2.27 mL 4.54 mL

*The above data is based on the productmolecular weight 440.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11787
CAS No. 54-62-6
Formula C19H20N8O5
M. Wt 440.4
Purity >98%
Synonyms 4-aminopteroic acid
SMILES C1=CC(=CC=C1C(=O)N[[email protected]@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Aminopterin | Aminopterin Supplier | purchase | cost | manufacturer | order | distributor | buy 54-62-6| 54-62-6 Supplier | purchase 54-62-6 | 54-62-6 cost | 54-62-6 manufacturer | order 54-62-6 | 54-62-6 distributor
Rewards