Amlodipine besylate (Norvasc)

Catalog No.: A10069

L-type calcium channel blocker

Amlodipine besylate (Norvasc) Chemical Structure

CAS NO. 111470-99-6

Amlodipine-besylate is L-type calcium channel blocker that displays antihypertensive properties. It inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease.

Availability: In stock

Package Price Qty
50 mg
$40.00
200 mg
$150.00
10mM * 1mL in DMSO
$64.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Amlodipine-besylate is L-type calcium channel blocker that displays antihypertensive properties. It inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease.
In vitro DMSO 113 mg/mL (199.27 mM)
Water <1 mg/mL (<1 mM)
Ethanol 14 mg/mL (24.68 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.63 mL 88.17 mL 176.34 mL
0.5 mM 3.53 mL 17.63 mL 35.27 mL
1 mM 1.76 mL 8.82 mL 17.63 mL
5 mM 0.35 mL 1.76 mL 3.53 mL

*The above data is based on the productmolecular weight 567.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10069
Actions Blocker
M. Wt 567.1
Formula C20H25ClN2O5.C6H6O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 111470-99-6
Synonyms Istin, Norvasc
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O

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