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|Storage||at -20°C 3 years Powder|
|Amlodipine-besylate is L-type calcium channel blocker that displays antihypertensive properties. It inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease.|
|Solubility (25°C)*||In vitro||DMSO||113 mg/mL (199.27 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||14 mg/mL (24.68 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||17.63 mL||88.17 mL||176.34mL|
|0.5 mM||3.53 mL||17.63 mL||35.27 mL|
|1 mM||1.76 mL||8.82 mL||17.63 mL|
|5 mM||0.35 mL||1.76 mL||3.53 mL|
*The above data is based on the productmolecular weight 567.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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