Amlodipine

Catalog No.: A10068
L-type calcium channel blocker
Amlodipin is L-type calcium channel blocker that displays antihypertensive properties. It inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease.
Grouped product items
Size Price Stock Qty
500mg
$40.00
In stock
1g
$65.00
In stock
5g
$300.00
In stock
10mM * 1mL in DMSO
$61.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription Amlodipin is L-type calcium channel blocker that displays antihypertensive properties. It inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
Product Information
Catalog Num A10068
Formula C20H25ClN2O5
Molecular Weight 408.9
CAS Number 88150-42-9
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
Synonyms Istin, Norvasc, Caduet
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 71 mg/mL (173.64 mM)
Water Insoluble
Ethanol 71 mg/mL (173.64 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.46 mL 122.28 mL 244.56 mL
0.5 mM 4.89 mL 24.46 mL 48.91 mL
1 mM 2.45 mL 12.23 mL 24.46 mL
5 mM 0.49 mL 2.45 mL 4.89 mL
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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