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Biological Activity
Amlodipin is L-type calcium channel blocker that displays antihypertensive properties. It inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease.
In vitro | DMSO | 71 mg/mL (173.64 mM) | |
Water | Insoluble | ||
Ethanol | 71 mg/mL (173.64 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.46 mL | 122.28 mL | 244.56 mL |
0.5 mM | 4.89 mL | 24.46 mL | 48.91 mL |
1 mM | 2.45 mL | 12.23 mL | 24.46 mL |
5 mM | 0.49 mL | 2.45 mL | 4.89 mL |
*The above data is based on the productmolecular weight 408.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10068 |
---|---|
Actions | Blocker |
CAS No. | 88150-42-9 |
Formula | C20H25ClN2O5 |
M. Wt | 408.9 |
Purity | >98% |
Synonyms | Istin, Norvasc, Caduet |
SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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