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$0.00 Biological Activity
Amphotericin B is a polyene antifungal antibiotic from Streptomyces sp. Amphotericin B induces K+ leakage, which is separate from its lethal action, as was demonstrated in human erythrocytes and is due to the inhibitory effect on the Na+/K+ pump.
Targets
| ergosterol | ||||
| In vitro | DMSO | 22 mg/mL (23.8 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 10.82 mL | 54.11 mL | 108.21 mL |
| 0.5 mM | 2.16 mL | 10.82 mL | 21.64 mL |
| 1 mM | 1.08 mL | 5.41 mL | 10.82 mL |
| 5 mM | 0.22 mL | 1.08 mL | 2.16 mL |
*The above data is based on the productmolecular weight 924.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10073 |
|---|---|
| Actions | No |
| M. Wt | 924.1 |
| Formula | C47H73NO17 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1397-89-3 |
| Synonyms | Fungilin, Fungizone, AmBisome, Fungisome, Amphocil, Amphotec |
| SMILES | C[[email protected]]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[[email protected]@H](C[[email protected]]2[[email protected]@H]([[email protected]](C[[email protected]](O2)(C[[email protected]](C[[email protected]]([[email protected]@H](CC[[email protected]](C[[email protected]](CC(=O)O[[email protected]]([[email protected]@H]([[email protected]@H]1O)C)C)O)O)O)O)O)O)O)C(=O)O)O[[email protected]]3[[email protected]]([[email protected]]([[email protected]@H]([[email protected]](O3)C)O)N)O |
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