AMPK Activator 2, a fluorine-containing proguanil derivative, targets the AMP-activated protein kinase (AMPK) signaling pathway, enhancing its activation while downregulating the mTOR/4EBP1/p70S6K pathway. This compound exhibits significant anti-proliferative and anti-migratory effects on various human cancer cell lines, including UMUC3, T24, and A549. AMPK Activator 2 is valuable for research focused on cancer metabolism and therapeutic strategies aimed at metabolic regulation in oncology.
AMPK Activator 2, a fluorine-containing proguanil derivative, targets the AMP-activated protein kinase (AMPK) signaling pathway, enhancing its activation while downregulating the mTOR/4EBP1/p70S6K pathway. This compound exhibits significant anti-proliferative and anti-migratory effects on various human cancer cell lines, including UMUC3, T24, and A549. AMPK Activator 2 is valuable for research focused on cancer metabolism and therapeutic strategies aimed at metabolic regulation in oncology.
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