Anetumab ravtansine is a potent antibody-drug conjugate (ADC) that specifically targets tubulin via a conjugation of a human anti-mesothelin antibody to the maytansinoid tubulin inhibitor DM4. This compound demonstrates significant antitumor activity, which correlates with mesothelin expression levels in patient-derived xenograft tumor models. Anetumab ravtansine is primarily used in cancer research, particularly in studies focusing on targeted therapies for mesothelin-expressing tumors.
Anetumab ravtansine is a potent antibody-drug conjugate (ADC) that specifically targets tubulin via a conjugation of a human anti-mesothelin antibody to the maytansinoid tubulin inhibitor DM4. This compound demonstrates significant antitumor activity, which correlates with mesothelin expression levels in patient-derived xenograft tumor models. Anetumab ravtansine is primarily used in cancer research, particularly in studies focusing on targeted therapies for mesothelin-expressing tumors.
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