Antazoline phosphate is a potent H1 receptor antagonist that primarily modulates the central nervous system and exhibits significant antiarrhythmic properties. This compound effectively prevents histamine from binding to its receptor sites, leading to antiallergic effects and inhibition of physiological responses triggered by histamine. In addition, Antazoline phosphate has demonstrated a dose-dependent reduction of HBV DNA in both HepAD38 and Huh7 cells, with EC50 values of 2.910 μmol/L and 2.349 μmol/L, respectively. Its multifaceted biological activity makes Antazoline phosphate valuable for research applications in cardiovascular diseases and hepatitis B virus studies.
Antazoline phosphate is a potent H1 receptor antagonist that primarily modulates the central nervous system and exhibits significant antiarrhythmic properties. This compound effectively prevents histamine from binding to its receptor sites, leading to antiallergic effects and inhibition of physiological responses triggered by histamine. In addition, Antazoline phosphate has demonstrated a dose-dependent reduction of HBV DNA in both HepAD38 and Huh7 cells, with EC50 values of 2.910 μmol/L and 2.349 μmol/L, respectively. Its multifaceted biological activity makes Antazoline phosphate valuable for research applications in cardiovascular diseases and hepatitis B virus studies.
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