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Apixaban (BMS-562247-01)

Catalog No.: A10082

Factor Xa inhibitor

Apixaban (BMS-562247-01)

Apixaban (BMS-562247-01) Chemical Structure

CAS NO. 503612-47-3

Apixaban is an anticoagulant for the prevention of venous thromboembolism and venous thromboembolic events.

Availability: In stock

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5 mg
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100 mg
10mM * 1mL in DMSO
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Daniël Verhoef, .et al. Engineered factor Xa variants retain procoagulant activity independent of direct factor Xa inhibitors, Nat Commun, 2017, 8: 528 PMID: 28904343

Biological Activity

Apixaban is an anticoagulant for the prevention of venous thromboembolism and venous thromboembolic events.
Factor Xa (human) (Cell-free assay) Factor Xa (rabbit) (Cell-free assay)
0.08 nM(Ki)0.17 nM(Ki)
In vitro (25°C) DMSO 17 mg/mL (36.99 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG 400+0.5% Tween 80+5% Propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.76 mL 108.81 mL 217.63 mL
0.5 mM 4.35 mL 21.76 mL 43.53 mL
1 mM 2.18 mL 10.88 mL 21.76 mL
5 mM 0.44 mL 2.18 mL 4.35 mL

*The above data is based on the productmolecular weight 459.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10082
Actions Inhibitor
CAS No. 503612-47-3
Formula C25H25N5O4
M. Wt 459.5
Purity >98%
Synonyms BMS-562247-01

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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