Total item
Cart Subtotal
$0.00 Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order
- Daniël Verhoef, .et al. Engineered factor Xa variants retain procoagulant activity independent of direct factor Xa inhibitors, Nat Commun, 2017, 8: 528 PMID: 28904343
Biological Activity
Apixaban is an anticoagulant for the prevention of venous thromboembolism and venous thromboembolic events.
Targets
| Factor Xa (human) (Cell-free assay) | Factor Xa (rabbit) (Cell-free assay) | |||
| 0.08 nM(Ki) | 0.17 nM(Ki) |
| In vitro (25°C) | DMSO | 17 mg/mL (36.99 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG 400+0.5% Tween 80+5% Propylene glycol | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.76 mL | 108.81 mL | 217.63 mL |
| 0.5 mM | 4.35 mL | 21.76 mL | 43.53 mL |
| 1 mM | 2.18 mL | 10.88 mL | 21.76 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.35 mL |
*The above data is based on the productmolecular weight 459.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10082 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 503612-47-3 |
| Formula | C25H25N5O4 |
| M. Wt | 459.5 |
| Purity | >98% |
| Synonyms | BMS-562247-01 |
| SMILES | COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy Apixaban (BMS-562247-01) | Apixaban (BMS-562247-01) Supplier | purchase | cost | manufacturer | order | distributor | buy 503612-47-3| 503612-47-3 Supplier | purchase 503612-47-3 | 503612-47-3 cost | 503612-47-3 manufacturer | order 503612-47-3 | 503612-47-3 distributor
Adooq Quality Guarantee
We promise all products perform as described.