Catalog No.: A13471

CCR5 entry inhibitor


Aplaviroc Chemical Structure

CAS NO. 461443-59-4

Aplaviroc is a CCR5 entry inhibitor developed for the treatment of HIV infection.

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Biological Activity

Aplaviroc is a CCR5 entry inhibitor developed for the treatment of HIV infection.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.31 mL 86.55 mL 173.1 mL
0.5 mM 3.46 mL 17.31 mL 34.62 mL
1 mM 1.73 mL 8.65 mL 17.31 mL
5 mM 0.35 mL 1.73 mL 3.46 mL

*The above data is based on the productmolecular weight 577.711. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13471
Actions Inhibitor
CAS No. 461443-59-4
Formula C33H43N3O6
M. Wt 577.711
Purity >98%
Synonyms AK 602, AK-602, GW 873140, GW873140, ONO 4128
SMILES CCCCN1C(=O)[[email protected]](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)O)[[email protected]@H](C5CCCCC5)O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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