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Apoptosis Activator 2

Apoptosis Activator 2

Name: Apoptosis Activator 2
Brand: Adooq Bioscience
SKU: A11944
Rating: 100 (268 reviews)

Catalog No.: A11944

Apoptosis Activator

Apoptosis Activator 2 Chemical Structure

CAS NO. 79183-19-0

Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells

Availability: In stock

Package	Price	Qty
10 mg	$50.00
25 mg	$110.00
50 mg	$180.00
100 mg	$285.00
10mM * 1mL in DMSO	$55.00
Custom Size	Get quote

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Adooq Products cited in reputable paper

Biological Activity

Targets

Caspase-3

Solubility *

In vitro	DMSO	53 mg/mL (173.12 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.67 mL	163.35 mL	326.69 mL
0.5 mM	6.53 mL	32.67 mL	65.34 mL
1 mM	3.27 mL	16.33 mL	32.67 mL
5 mM	0.65 mL	3.27 mL	6.53 mL

*The above data is based on the productmolecular weight 306.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A11944
Actions	Activator
CAS No.	79183-19-0
Formula	C15H9Cl2NO2
M. Wt	306.1
Purity	>98%
SMILES	C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC(=C(C=C3)Cl)Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.