Apoptosis Activator 2

Catalog No.: A11944

Apoptosis Activator

Apoptosis Activator 2

Apoptosis Activator 2 Chemical Structure

CAS NO. 79183-19-0

Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells

Availability: In stock

Package Price Qty
10 mg
$50.00
25 mg
$110.00
50 mg
$180.00
100 mg
$285.00
10mM * 1mL in DMSO
$55.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells
Targets
Caspase-3
In vitro DMSO 61 mg/mL (199.25 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.67 mL 163.35 mL 326.69 mL
0.5 mM 6.53 mL 32.67 mL 65.34 mL
1 mM 3.27 mL 16.33 mL 32.67 mL
5 mM 0.65 mL 3.27 mL 6.53 mL

*The above data is based on the productmolecular weight 306.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11944
Actions Activator
M. Wt 306.1
Formula C15H9Cl2NO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 79183-19-0
Synonyms N/A
SMILES C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC(=C(C=C3)Cl)Cl

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