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Biological Activity
Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) .
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.13 mL | 120.63 mL | 241.25 mL |
| 0.5 mM | 4.83 mL | 24.13 mL | 48.25 mL |
| 1 mM | 2.41 mL | 12.06 mL | 24.13 mL |
| 5 mM | 0.48 mL | 2.41 mL | 4.83 mL |
*The above data is based on the productmolecular weight 414.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13330 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 287405-51-0 |
| Formula | C17H22N2O6S2 |
| M. Wt | 414.5 |
| Purity | >98% |
| SMILES | CC1(C)[C@H](C(NO)=O)N(S(=O)(C2=CC=C(OCC#CCO)C=C2)=O)CCS1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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