Aquacobalamin

Catalog No.: A73256
Endogenous Metabolite
Aquacobalamin is a biologically active form of vitamin B12, primarily functioning as a cofactor in various enzymatic reactions. It enhances the oxidation of azo-dye Orange II in the presence of hydrogen persulfate, demonstrating its potential as a catalyst in oxidative reactions. Additionally, Aquacobalamin binds reversibly to hydrogen peroxide, forming a cobalt(III) hydroperoxo adduct with a dissociation constant of 0.25 mM, contributing to its diverse applications in biochemical research and oxidative stress studies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAquacobalamin is a biologically active form of vitamin B12, primarily functioning as a cofactor in various enzymatic reactions. It enhances the oxidation of azo-dye Orange II in the presence of hydrogen persulfate, demonstrating its potential as a catalyst in oxidative reactions. Additionally, Aquacobalamin binds reversibly to hydrogen peroxide, forming a cobalt(III) hydroperoxo adduct with a dissociation constant of 0.25 mM, contributing to its diverse applications in biochemical research and oxidative stress studies.
Product Information
Catalog NumA73256
FormulaC62H90CoN13O16P
Molecular Weight1363.36
CAS Number13422-52-1
SMILESO[Co+3]1234-;@[N]5=;@C6-;@C(C)=;@C(-;@C(CC(N)=O)(C)-;@C-;@7CCC(N)=O)-;@[N]-;@1=;@C7-;@C=;@C(-;@C(C)(C)-;@C-;@8CCC(N)=O)-;@[N]-;@2=;@C8-;@C(C)=;@C(-;@C(C)(-;@C-;@C-;@C(-;@N-;@C-;@C(C)-;@O-;@P(-;@O-;@C9-;@C(O)-;@C(-;@O-;@C-;@9CO)-;@N%10-;@C=;@[N]-;@4-;@C%11=;@C-;@%10-;@C=;@C(C)-;@C(C)=;@C-;@%11)([O-])=O)=O)-;@C-;@%12CC(N)=O)-;@[N-]-;@3-;@C%12-;@C-;@5(C)-;@C(CC(N)=O)(C)-;@C-;@6CCC(N)=O.[OH-]
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