AR Antagonist 11 is a selective androgen receptor (AR) antagonist with an IC50 of 0.019 μM. It also demonstrates efficacy against the ARF877L/T878A mutant with an IC50 of 1.03 μM. AR Antagonist 11 effectively inhibits LNCaP cell proliferation and reduces PSA protein expression, with an IC50 of 0.54 μM. This compound is suitable for research into prostate cancer (PCa) biology and therapeutic strategies.
AR Antagonist 11 is a selective androgen receptor (AR) antagonist with an IC50 of 0.019 μM. It also demonstrates efficacy against the ARF877L/T878A mutant with an IC50 of 1.03 μM. AR Antagonist 11 effectively inhibits LNCaP cell proliferation and reduces PSA protein expression, with an IC50 of 0.54 μM. This compound is suitable for research into prostate cancer (PCa) biology and therapeutic strategies.
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