AR Antagonist 3 is a selective androgen receptor (AR) antagonist with a measured IC50 of 0.47 µM, demonstrating strong potency in blocking AR activity. It effectively reduces FRET signal in a dose-dependent manner, with an IC50 of 18.05 μM. In preclinical studies, AR Antagonist 3 has shown significant inhibition of tumor growth upon intratumoral administration, making it a valuable tool for research in androgen receptor-related cancer therapies.
AR Antagonist 3 is a selective androgen receptor (AR) antagonist with a measured IC50 of 0.47 µM, demonstrating strong potency in blocking AR activity. It effectively reduces FRET signal in a dose-dependent manner, with an IC50 of 18.05 μM. In preclinical studies, AR Antagonist 3 has shown significant inhibition of tumor growth upon intratumoral administration, making it a valuable tool for research in androgen receptor-related cancer therapies.
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