Total item
Cart Subtotal
$0.00 - Hamzehlou S, .et al. Anti-tumor activity of neratinib, a pan-HER inhibitor, in gastric adenocarcinoma cells, Eur J Pharmacol, 2019, Nov 15;863:172705 PMID: 31574259
Biological Activity
ARRY334543 is a potent, orally active small molecule inhibitor of EGFR and ErbB-2.
| In vitro | DMSO | 6 mg/mL (12.84 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.42 mL | 107.08 mL | 214.16 mL |
| 0.5 mM | 4.28 mL | 21.42 mL | 42.83 mL |
| 1 mM | 2.14 mL | 10.71 mL | 21.42 mL |
| 5 mM | 0.43 mL | 2.14 mL | 4.28 mL |
*The above data is based on the productmolecular weight 466.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11158 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 466.94 |
| Formula | C22H19ClN6O2S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 845272-21-1 |
| Synonyms | ARRY-334543, Varlitinib |
| SMILES | C1=CC=C(C=C1)C[N+]2=C(N=C(S2)NC3=CC=CC=C3)C4=CC=CC=C4 |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
Canertinib (CI-1033)
Canertinib (CI-1033) is an irreversible tyrosine-kinase inhibitor with activity against EGFR (IC50 0.8 nM), HER-2 (IC50 19 nM) and ErbB-4 (I…
BIBX 1382
BIBX 1382 is a cell-permeable pyrimidopyrimidine compound that acts as a potent, reversible, ATP-competitive, and highly selective inhibitor…
Chrysophanic acid (Chrysophanol)
Chrysophanic acid (Chrysophanol) blocks proliferation of colon cancer cells by inhibiting EGFR/mTOR pathway.
CP-724714
CP-724714 is an orally available, small molecule, potent HER-2 tyrosine kinase inhibitor that inhibits HER2 kinase (IC50 3.8 ng/ml) .
BIBW2992 (Afatinib)
BIBW2992 (Afatinib) is tyrosine kinase inhibitor (TKI) that irreversibly inhibits human epidermal growth factor receptor 2 (Her2) and epider…
BMS-690514
BMS-690514 is a potent and selective inhibitor of epidermal growth factor receptor (EGFR), HER2, and HER4, as well as the VEGF receptor kina…
BMS 599626 (AC480)
BMS 599626 is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50=22, 32 and 190 nM, respectively) with poten…
Erlotinib HCl
Erlotinib hydrochloride is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).
Keywords:buy ARRY334543 (Varlitinib) | ARRY334543 (Varlitinib) Supplier | purchase | cost | manufacturer | order | distributor | buy 845272-21-1| 845272-21-1 Supplier | purchase 845272-21-1 | 845272-21-1 cost | 845272-21-1 manufacturer | order 845272-21-1 | 845272-21-1 distributor
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: [email protected]
Not your Region? View all Distributors
Adooq Quality Guarantee
We promise all products perform as described.