ARRY334543 (Varlitinib)

ARRY334543 is a potent, orally active small molecule inhibitor of EGFR and ErbB-2.
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ARRY334543 5mg
ARRY334543 10mg
ARRY334543 50mg
ARRY334543 200mg
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Adooq Products cited in reputable paper
Adooq's ARRY334543 (Varlitinib) has been cited by 1 publications
  • Hamzehlou S, .et al. , Eur J Pharmacol, 2019, Nov 15;863:172705 PMID: 31574259
  • Biological Activity
    Discription ARRY334543 is a potent, orally active small molecule inhibitor of EGFR and ErbB-2.
    Product Information
    Catalog Num A11158
    Formula C22H19ClN6O2S
    Molecular Weight 466.94
    CAS Number 845272-21-1
    SMILES C[C@@H]1COC(=N1)NC2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=NC=CS5)Cl
    Synonyms ARRY-334543, Varlitinib

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro DMSO 6 mg/mL (12.84 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.42 mL 107.08 mL 214.16 mL
    0.5 mM 4.28 mL 21.42 mL 42.83 mL
    1 mM 2.14 mL 10.71 mL 21.42 mL
    5 mM 0.43 mL 2.14 mL 4.28 mL
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