ARRY334543 (Varlitinib)

Name: ARRY334543 (Varlitinib)
SKU: A11158
Price: 120 USD
Rating: 5 (1 reviews)

Catalog No.: A11158

EGFR inhibitor

Adooq's ARRY334543 (Varlitinib) has been cited by 1 publications

ARRY334543 is a potent, orally active small molecule inhibitor of EGFR and ErbB-2.

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's ARRY334543 (Varlitinib) has been cited by 1 publications

Hamzehlou S, .et al. , Eur J Pharmacol, 2019, Nov 15;863:172705 PMID: 31574259

Biological Activity

Discription	ARRY334543 is a potent, orally active small molecule inhibitor of EGFR and ErbB-2.

Chemical Information

Catalog Num	A11158
Formula	C22H19ClN6O2S
Molecular Weight	466.94
CAS Number	845272-21-1
SMILES	C[C@@H]1COC(=N1)NC2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=NC=CS5)Cl
Synonyms	ARRY-334543, Varlitinib
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	6 mg/mL (12.84 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.42 mL	107.08 mL	214.16 mL
0.5 mM	4.28 mL	21.42 mL	42.83 mL
1 mM	2.14 mL	10.71 mL	21.42 mL
5 mM	0.43 mL	2.14 mL	4.28 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Product Name	Price	Stock
ARRY334543 5mg	$120.00	In stock
ARRY334543 10mg	$190.00	In stock
ARRY334543 50mg	$470.00	In stock
ARRY334543 200mg	$1,860.00	In stock

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