Artesunate

Catalog No.: A10087

cytochrome oxidase inhibitor

Artesunate

Artesunate Chemical Structure

CAS NO. 88495-63-0

Artesunate is a semisynthetic derivative of artemisinin used to treat malaria. It has also been shown to effective against other parasites such as liver flukes. Artesunate also demonstrates cytotoxic action against cancer cell lines of different tumor types. Artesunate has been shown to inhibit TNF--induced production of proinflammatory cytokines via inhibition of NF-B and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $40.00

Special Price $36.00

50 mg

Regular Price: $160.00

Special Price $144.00

100 mg

Regular Price: $280.00

Special Price $252.00

10mM * 1mL in DMSO

Regular Price: $74.00

Special Price $66.60

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Artesunate is a semisynthetic derivative of artemisinin used to treat malaria. It has also been shown to effective against other parasites such as liver flukes. Artesunate also demonstrates cytotoxic action against cancer cell lines of different tumor types. Artesunate has been shown to inhibit TNF--induced production of proinflammatory cytokines via inhibition of NF-B and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes.
Targets
EXP1(a membrane glutathione S-transferase)
In vitro DMSO 77 mg/mL (200.3 mM)
Water <1 mg/mL (<1 mM)
Ethanol 77 mg/mL (200.3 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.01 mL 130.07 mL 260.15 mL
0.5 mM 5.2 mL 26.01 mL 52.03 mL
1 mM 2.6 mL 13.01 mL 26.01 mL
5 mM 0.52 mL 2.6 mL 5.2 mL

*The above data is based on the productmolecular weight 384.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10087
Actions Inhibitor
M. Wt 384.4
Formula C19H28O8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 88495-63-0
Synonyms N/A
SMILES C[[email protected]@H]1CC[[email protected]]2[[email protected]]([[email protected]@H](O[[email protected]]3[[email protected]@]24[[email protected]]1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C

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