AS1842856

Catalog No.: A15871

Foxo1 Inhibitor

AS1842856

AS1842856 Chemical Structure

CAS NO. 836620-48-5

AS1842856 is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM. It could directly bind to the active Foxo1, but not the Ser256-phosphorylated form.

Availability: In stock

Package Price Qty
10 mg
$110.00
25 mg
$250.00
50 mg
$450.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AS1842856 is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM. It could directly bind to the active Foxo1, but not the Ser256-phosphorylated form.
Targets
Foxo1
33nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.79 mL 143.93 mL 287.87 mL
0.5 mM 5.76 mL 28.79 mL 57.57 mL
1 mM 2.88 mL 14.39 mL 28.79 mL
5 mM 0.58 mL 2.88 mL 5.76 mL

*The above data is based on the productmolecular weight 347.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15871
Actions Inhibitor
M. Wt 347.38
Formula C18H22FN3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 836620-48-5
Synonyms AS 1842856, AS-1842856
SMILES O=C1C(C(O)=O)=CN(CC)C2=C1C(N)=C(F)C(NC3CCCCC3)=C2

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