AS1842856

Catalog No.: A15871
Foxo1 Inhibitor
AS1842856 is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM. It could directly bind to the active Foxo1, but not the Ser256-phosphorylated form.
Grouped product items
Product Name Price Stock Qty
AS1842856 10mg
$80.00
In stock
AS1842856 25mg
$130.00
In stock
AS1842856 50mg
$175.00
In stock
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Adooq Products cited in reputable paper
Adooq's AS1842856 has been cited by 2 publications
  • Yuta Tanizaki, .et al. , Commun Biol, 2022, 5: 112 PMID: 35132135
  • Zhongsheng Zhu, .et al. , BMC Complement Altern Med, 2019, 19: 111 PMID: 31146723
  • Biological Activity
    Discription AS1842856 is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM. It could directly bind to the active Foxo1, but not the Ser256-phosphorylated form.
    Targets
    Target Value
    Product Information
    Catalog Num A15871
    Formula C18H22FN3O3
    Molecular Weight 347.38
    CAS Number 836620-48-5
    SMILES O=C1C(C(O)=O)=CN(CC)C2=C1C(N)=C(F)C(NC3CCCCC3)=C2
    Synonyms AS 1842856, AS-1842856
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 23 mg/mL (66.2 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 28.79 mL 143.93 mL 287.87 mL
    0.5 mM 5.76 mL 28.79 mL 57.57 mL
    1 mM 2.88 mL 14.39 mL 28.79 mL
    5 mM 0.58 mL 2.88 mL 5.76 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

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