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Biological Activity
ASP9521 is a novel, selective, orally bioavailable inhibitor of 17??-hydroxysteroid dehydrogenase type 5 (17bHSD5, AKR1C3).
| In vitro | DMSO | 65 mg/mL (196.71 mM) | |
| Water | Insoluble | ||
| Ethanol | 65 mg/mL (196.71 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.26 mL | 151.32 mL | 302.65 mL |
| 0.5 mM | 6.05 mL | 30.26 mL | 60.53 mL |
| 1 mM | 3.03 mL | 15.13 mL | 30.26 mL |
| 5 mM | 0.61 mL | 3.03 mL | 6.05 mL |
*The above data is based on the productmolecular weight 330.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14412 |
|---|---|
| CAS No. | 1126084-37-4 |
| Formula | C19H26N2O3 |
| M. Wt | 330.42 |
| Purity | >98% |
| Synonyms | ASP-9521, ASP 9521, AKR1C3 inhibitor, 17??HSD5 inhibitor |
| SMILES | O=C(N1CCC(CC(C)(O)C)CC1)C(N2)=CC3=C2C=CC(OC)=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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