AT-101

Catalog No.: A15004

Bcl-2 Inhibitor

AT-101

AT-101 Chemical Structure

CAS NO. 90141-22-3

AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32μM, 0.48μM and 0.18μM.

Availability: In stock

Package Price Qty
10 mg
$80.00
50 mg
$330.00
100 mg
$660.00
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Biological Activity

AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32μM, 0.48μM and 0.18μM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.28 mL 96.42 mL 192.85 mL
0.5 mM 3.86 mL 19.28 mL 38.57 mL
1 mM 1.93 mL 9.64 mL 19.28 mL
5 mM 0.39 mL 1.93 mL 3.86 mL

*The above data is based on the productmolecular weight 518.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15004
Actions Inhibitor
M. Wt 518.55
Formula C30H30O8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 90141-22-3
Synonyms (R)-(-)-Gossypol, R-(-)-gossypol acetic acid, AT 101, AT101
SMILES CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C

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