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Acetate gossypol, a polyphenolic compound isolated from cottonseeds, inhibits Bcl-2 by acting as a BH3 mimetic.
Targets
| Dehydrogenase | Bcl2 | |||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.28 mL | 86.41 mL | 172.83 mL |
| 0.5 mM | 3.46 mL | 17.28 mL | 34.57 mL |
| 1 mM | 1.73 mL | 8.64 mL | 17.28 mL |
| 5 mM | 0.35 mL | 1.73 mL | 3.46 mL |
*The above data is based on the productmolecular weight 578.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A14795 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 578.61 |
| Formula | C32H34O10 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 12542-36-8 |
| Synonyms | Gossypol-acetic acid |
| SMILES | CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C.CC(=O)O |
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