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(S)-Gossypol acetic acid

Bcl-2 inhibitor

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Catalog No. A16323

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
(S)-Gossypol acetic acid 5mg A16323-5
$80.00
(S)-Gossypol acetic acid 10mg A16323-10
$140.00
(S)-Gossypol acetic acid 50mg A16323-50
$400.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

(S)-Gossypol acetic acid is a inhibitor of Bcl-2, potently induce cell death in Jurkat cells overexpressing Bcl-2 (IC50, 18.1μM) or Bcl-xL (IC50, 22.9μM).

(S)-Gossypol acetic acid

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Chemical Information

Catalog Num A16323
Actions Inhibitor
M. Wt 578.61
Formula C32H34O10
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1189561-66-7
Synonyms (S)-(+)-Gossypol acetic acid
SMILES CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C.CC(=O)O

Biological Activity

Description
(S)-Gossypol acetic acid is a inhibitor of Bcl-2, potently induce cell death in Jurkat cells overexpressing Bcl-2 (IC50, 18.1μM) or Bcl-xL (IC50, 22.9μM).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.28 mL 86.41 mL 172.83mL
0.5 mM 3.46 mL 17.28 mL 34.57 mL
1 mM 1.73 mL 8.64 mL 17.28 mL
5 mM 0.35 mL 1.73 mL 3.46 mL

*The above data is based on the productmolecular weight 578.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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