(S)-Gossypol acetic acid

Catalog No.: A16323

(S)-Gossypol acetic acid

(S)-Gossypol acetic acid Chemical Structure

CAS NO. 1189561-66-7

(S)-Gossypol acetic acid is a inhibitor of Bcl-2, potently induce cell death in Jurkat cells overexpressing Bcl-2 (IC50, 18.1μM) or Bcl-xL (IC50, 22.9μM).

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$140.00
50 mg
$400.00
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Biological Activity

(S)-Gossypol acetic acid is a inhibitor of Bcl-2, potently induce cell death in Jurkat cells overexpressing Bcl-2 (IC50, 18.1μM) or Bcl-xL (IC50, 22.9μM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.28 mL 86.41 mL 172.83 mL
0.5 mM 3.46 mL 17.28 mL 34.57 mL
1 mM 1.73 mL 8.64 mL 17.28 mL
5 mM 0.35 mL 1.73 mL 3.46 mL

*The above data is based on the productmolecular weight 578.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16323
Actions Inhibitor
CAS No. 1189561-66-7
Formula C32H34O10
M. Wt 578.61
Purity >98%
Synonyms (S)-(+)-Gossypol acetic acid
SMILES CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C.CC(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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