(S)-Gossypol acetic acid

Catalog No.: A16323

(S)-Gossypol acetic acid

(S)-Gossypol acetic acid Chemical Structure

CAS NO. 1189561-66-7

(S)-Gossypol acetic acid is a inhibitor of Bcl-2, potently induce cell death in Jurkat cells overexpressing Bcl-2 (IC50, 18.1μM) or Bcl-xL (IC50, 22.9μM).

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$140.00
50 mg
$400.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

(S)-Gossypol acetic acid is a inhibitor of Bcl-2, potently induce cell death in Jurkat cells overexpressing Bcl-2 (IC50, 18.1μM) or Bcl-xL (IC50, 22.9μM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.28 mL 86.41 mL 172.83 mL
0.5 mM 3.46 mL 17.28 mL 34.57 mL
1 mM 1.73 mL 8.64 mL 17.28 mL
5 mM 0.35 mL 1.73 mL 3.46 mL

*The above data is based on the productmolecular weight 578.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A16323
Actions Inhibitor
M. Wt 578.61
Formula C32H34O10
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1189561-66-7
Synonyms (S)-(+)-Gossypol acetic acid
SMILES CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C.CC(=O)O

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