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Publications citing Adooq Products
Chemical Information
| Catalog Num | A10094 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 337.9 |
| Formula | C20H20ClN3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 857531-00-1 |
| Synonyms | AT-7867 |
| SMILES | C1CNCCC1(C2=CC=C(C=C2)C3=CNN=C3)C4=CC=C(C=C4)Cl |
Description |
AT7867 is a novel and potent inhibitor of both AKT and the downstream kinase p70 S6 kinase (p70S6K) and also of protein kinase A. | ||||||||||||||||||||||||||||||||||||||||
Targets |
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| Solubility (25°C) * | In vitro | DMSO | 68 mg/mL (201.27 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 5 mg/mL (14.79 mM) | ||
| In vivo | 15% Captisol, pH 9 | 10 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.59 mL | 147.97 mL | 295.95mL |
| 0.5 mM | 5.92 mL | 29.59 mL | 59.19 mL |
| 1 mM | 2.96 mL | 14.8 mL | 29.59 mL |
| 5 mM | 0.59 mL | 2.96 mL | 5.92 mL |
*The above data is based on the productmolecular weight 337.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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