Signaling Pathway
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| Discription | AT7867 is a novel and potent inhibitor of both AKT and the downstream kinase p70 S6 kinase (p70S6K) and also of protein kinase A. | ||
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| Targets |
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| Catalog Num | A10094 |
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| Formula | C20H20ClN3 |
| Molecular Weight | 337.9 |
| CAS Number | 857531-00-1 |
| SMILES | C1CNCCC1(C2=CC=C(C=C2)C3=CNN=C3)C4=CC=C(C=C4)Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 63 mg/mL (186.47 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (14.79 mM) | ||
| In vivo | 15% Captisol, pH 9 | 9 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.59 mL | 147.97 mL | 295.95 mL |
| 0.5 mM | 5.92 mL | 29.59 mL | 59.19 mL |
| 1 mM | 2.96 mL | 14.8 mL | 29.59 mL |
| 5 mM | 0.59 mL | 2.96 mL | 5.92 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
