Atazanavir-d5 is a deuterium-labeled derivative of Atazanavir, a highly selective inhibitor of HIV-1 protease. This compound serves as a substrate and inhibitor of the cytochrome P450 enzyme CYP3A4, as well as an inhibitor and inducer of P-glycoprotein (P-gp). Additionally, Atazanavir exhibits activity against SARS-CoV 3CLpro with an IC50 of 3.49 μM, making it valuable for research into HIV and coronavirus-related mechanisms.
Atazanavir-d5 is a deuterium-labeled derivative of Atazanavir, a highly selective inhibitor of HIV-1 protease. This compound serves as a substrate and inhibitor of the cytochrome P450 enzyme CYP3A4, as well as an inhibitor and inducer of P-glycoprotein (P-gp). Additionally, Atazanavir exhibits activity against SARS-CoV 3CLpro with an IC50 of 3.49 μM, making it valuable for research into HIV and coronavirus-related mechanisms.
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