Atecegatran is an orally active competitive thrombin inhibitor targeting thrombin with a Ki value of 2-4 nM. By blocking thrombin's interaction with fibrin and thrombomodulin, it effectively inhibits platelet activation and aggregation. Demonstrating significant anticoagulant properties, Atecegatran exhibits an IC50 range of 93 to 220 nM in various plasma coagulation assays. This reagent is valuable for research focused on thromboembolic disorders and related cardiovascular studies.
Atecegatran is an orally active competitive thrombin inhibitor targeting thrombin with a Ki value of 2-4 nM. By blocking thrombin's interaction with fibrin and thrombomodulin, it effectively inhibits platelet activation and aggregation. Demonstrating significant anticoagulant properties, Atecegatran exhibits an IC50 range of 93 to 220 nM in various plasma coagulation assays. This reagent is valuable for research focused on thromboembolic disorders and related cardiovascular studies.
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